Abstract: Sodium-ion battery is one of the most popular secondary ion batteries studied in recent years, which has the advantages of low cost and abundant resources. However, the large atomic mass and ionic radius of sodium lead to structural deformation of sodium-ion batteries, which affects their electrochemical performance. MXene is a novel two-dimensional layered structural material with high conductivity, high plasticity, high corrosion resistance, and large specific surface area, which has been widely used in sodium-ion batteries. However, when MXene is used as an electrode material, their layers are easy to re-stacked due to the van der Waals force between the layers, which reduces the surface-active sites and lengthens the ion diffusion paths, thus affecting the specific capacity and rate performance of sodium-ion batteries. This paper reviews the research progress of MXene as anodes of sodium-ion batteries. It introduces the basic properties and preparation methods of MXene, discusses the modification and optimization methods and the sodium storage mechanism of MXene in detail. It also summarizes the difficulties and challenges faced by MXene in the practical application as anodes of sodium-ion batteries and looks forward to the direction of further development of MXene. It is hoped that this will strengthen the practical application of MXene.